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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Small nucleolar RNA SNORD44 ： ウィキペディア英語版 Small nucleolar RNA SNORD44 snoRNA U44 (also known as SNORD44) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA U44 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. U44 was originally cloned from HeLa cells and expression verified by northern blotting. It is predicted to guide 2'O-ribose methylation of 18S ribosomal RNA(rRNA) at residue A166. In the human genome, U44 is located in the same gene as several other C/D box snoRNAs (U47, U74, U75, U76, U77, U78, U79, U80 and U81).〔 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Small nucleolar RNA SNORD44」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.